Tretinoin (Retin-A)

Tretinoin is a safe and effective topical treatment premature aging of the skin. Tretinoin has been proven to improved mild sun damage, fine wrinkles and discoloration if used as part of with a comprehensive skin care program.

Tretinoin is a derivative of vitamin A. It works to alter the skin cells by modulating gene expression, rather than inducing cell necrosis (death). The effect of tretinoin is the speeding of skin cell turnover, reducing breakouts and producing smoother, younger looking skin. Melanocytes, the skin cells responsible for skin pigment, are suppressed by tretinoin. This decreases skin discoloration and uneven skin tone. As a result, fine lines and wrinkles are reduced, skin feels smoother and looks more evenly colored.

While many people know Retin-A for its effectiveness in the treatment of severe acne, other uses have been found. It is important to understand what this medication can and cannot do for your skin. Tretinoin cannot reverse severe skin damage, wrinkling or advanced sun damage.

Tretinoin is a prescription medication, which requires an order from your physician. It is marketed by various of pharmaceutical companies as Altinac™; Avita®; RENOVA®; Retin-A™; Retin-A® Micro. Use tretinoin exactly as prescribed by your doctor. The usual regimen is once daily application of a thin film to the face prior to bedtime. Make sure to avoid sensitive skin on the lips and under the eye area. For more sensitive skin, your doctor may recommend every other or every third day application.

Application of more than the recommended amount will not provide faster or better results. Overuse is likely to cause more skin irritation. Gel preparation of this medication seems to give better results as it can penetrate the skin more. While undergoing a skin regime using tretinoin, you can wear make up, but be sure to clean your face thoroughly before using your medication.

Exposure to sunlight (including sunlamps) should be avoided or minimized during use of Tretinoin Cream, USP (Emollient), because of heightened sunburn susceptibility. Patients should be warned to use sunscreens (minimum SPF of 15) and protective clothing when using Tretinoin Cream, USP (Emollient). Patients with sunburn should be advised not to use Tretinoin Cream, USP (Emollient) until fully recovered. Patients who may have considerable sun exposure, e.g., due to their occupation and those patients with inherent sensitivity to sunlight, should exercise caution when using Tretinoin Cream, USP (Emollient) and follow the precautions outlined in the Patient Package Insert.